Topiramate for essential tremor
نویسندگان
چکیده
منابع مشابه
Efficacy and Safety of Topiramate for Essential Tremor
Essential tremor (ET) is the most common movement disorder that is frequently treated by propranolol or primidone. However, 30% of patients with ET do not respond to either propranolol or primidone. The objective of this study was to assess the efficacy and safety of topiramate for ET.We searched the MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials for relevant randomized...
متن کاملZonisamide for essential tremor.
OBJECTIVE The pharmacological therapy for essential tremor (ET) is inadequate, and many patients resort to surgical procedures. Zonisamide is an antiepileptic with several potential mechanisms of action. MATERIALS AND METHODS We evaluated zonisamide for ET in an open-label pilot trial. The primary efficacy point was the change in the Tremor Study Group rating scale (TSGRS) scores. RESULTS T...
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This case report demonstrates a satisfying response to topiramate in a 79-year-old patient with disabling essential tremor in whom propranolol as well as primidone had to be discontinued due to severe side effects. After 28 months of topiramate treatment, a clear decline in Mini Mental State Examination (MMSE) could be observed, stressing the use of care in prescribing topiramate in elderly pat...
متن کاملEssential tremor
Methods Seventy-two patients with severe, medication-refractory essential tremor have been enrolled across seven international centers. Standard assessments of tremor severity and disability will be obtained before and after the procedure. Patients are randomized in a one-to-three fashion to receive either sham procedure or MR-guided focused ultrasound thalamotomy. The Tremor Research Group, ne...
متن کاملKnowledge about Essential Tremor: A Study of Essential Tremor Families
Background Essential tremor (ET) is among the most common neurological diseases and it often runs in families. How knowledgeable ET patients and their families are about their disease has been the subject of surprisingly little scholarship. Methods To fill this gap in knowledge, we administered a comprehensive 32-item survey (i.e., questions about etiology, pathophysiology, symptoms and signs...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2017
ISSN: 1465-1858
DOI: 10.1002/14651858.cd009683.pub2